Data of the effects of acetone fraction from Sechium edule (Jacq.) S.w. edible roots in the kidney of endothelial dysfunction induced mice.

Abstract

Endothelial dysfunction induced by Angiotensin II (AG II) plays an important role in the pathogenesis of hypertension and is accompanied by a prooxidative condition, which in turn induces an inflammatory state, vascular remodeling, and tissue damage including the kidney (Schmitt and Dirsch, 2009) [1]. New drugs that can control several of these pathologies are required. Sechium edule has been reported to possess antioxidant, anti-inflammatory and antihypertensive activity (Ibarra-Alvarado et al., 2010) [2]. This paper contains data complementary to those published in Journal of Ethnopharmacology (Moreno et al., 2018) [3], evaluating the effect in kidney of hypertensive mice of the acetone fraction from S. edule to control de pro-oxidative state, reduction of the inflammatory adhesion molecule (ICAM) and recruitment of inflammatory cells.

• Authors: Celeste Trejo-Moreno, Gabriela Castro-Martínez, Marisol Méndez-Martínez, Jesús Enrique Jiménez-Ferrer, José Pedraza-Chaverri, Gerardo Arrellín, Alejandro Zamilpa-Álvarez, Omar Noel Medina-Campos, Galia Lombardo-Earl, Gerardo Joel Barrita-Cruz, Beatriz Hernández, Christian Carlos Ramírez, María Angélica Santana, Gladis Fragoso, Gabriela Rosas
• Journal: Data in brief (Data Brief) Vol. 18 Pg. 448-453 (Jun 2018) ISSN: 2352-3409 [Print] Netherlands
• PMID: 29900200 (Publication Type: Journal Article)