[Case Report - Metamizole-Induced Agranulocytosis].

Abstract

Metamizole is primarily used for severe perioperative pain, acute injury and colic, and cancer pain. For other acute/chronic forms of pain and high fever, it should only be used if unresponsive to other agents. Metamizole should not be used for middle and low pain. Oral application should be preferred. A contraindication for metamizole is leukopenia. Clinical signs for agranulocytosis are fever, tonsillitis and aphthous stomatitis.

• Authors: Falk A Gonnert, Winfried Meißner
• Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS (Anasthesiol Intensivmed Notfallmed Schmerzther) Vol. 53 Issue 5 Pg. 388-394 (May 2018) ISSN: 1439-1074 [Electronic] Germany
• Vernacular Title: Kasuistik: Metamizol-induzierte Agranulozytose.
• PMID: 29772595 (Publication Type: Case Reports, Journal Article)
• Copyright: Georg Thieme Verlag KG Stuttgart · New York.

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Dipyrone

Topics

• Aged
• Agranulocytosis (blood, chemically induced)
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects)
• Arthroplasty, Replacement, Hip
• Dipyrone (adverse effects)
• Fatal Outcome
• Humans
• Hypertension (complications)
• Leukopenia (blood, chemically induced)
• Male
• Multiple Organ Failure (blood, chemically induced)
• Shock, Septic (complications, drug therapy)