Abstract | AIM:: MATERIAL AND METHODS:: An open non-comparative observational study of the continuous use of S. repens plant extract at a dosage of 320 mg once a day for 15 years was performed in 30 patients at risk for benign prostatic hyperplasia progression. Changes in IPSS (International Prostatic Symptoms Scale) and QoL (Quality of life) scores and changes in Qmax, voided volume, residual urine volume, and prostate volume were evaluated during the study. RESULTS:: The study showed an absence of progression based on both subjective (the sum of scores on the IPSS and QoL scales) and objective (prostate volume, urination rate, residual urine volume) criteria. Furthermore, the patients had no adverse events related to the study drug, including prostate cancer. CONCLUSIONS::
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Authors | Andrey Zinovievich Vinarov, Leonid Grigorievich Spivak, Darina Vladimirovna Platonova, Leonid Mikhailovich Rapoport, Dmitry Olegovich Korolev |
Journal | Urologia
(Urologia)
Vol. 86
Issue 1
Pg. 17-22
(Feb 2019)
ISSN: 1724-6075 [Electronic] United States |
PMID | 29741118
(Publication Type: Journal Article, Observational Study)
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Chemical References |
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Topics |
- Disease Progression
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Phytotherapy
- Plant Extracts
(adverse effects, therapeutic use)
- Prostatic Hyperplasia
(drug therapy)
- Serenoa
- Time Factors
- Treatment Outcome
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