Orthodontics and Moebius syndrome: an observational study.

Abstract

BACKGROUND:

Moebius syndrome is a rare condition characterized by bilateral facial and abducens nerve paralysis. The aim of this study is to evaluate the main orthodontic features and the frequency of associated clinical characteristics in patients with Moebius syndrome (MS).

METHODS:

According to Terzis classifications, 58 patients with MS aged 8 months to 46 years old underwent orthodontics and clinical examination.

RESULTS:

Strabismus, upper and lower limb malformations, lip and palatal cleft were frequently associated with MS. Reduced TM movements were noted (48%). Cephalometric analysis did not allow identifying a typical facies and a characteristic cephalometric pattern; we have noticed a higher prevalence of Class II (56%) with micrognathia and excessive maxillary development probably due to the lack of lip seal. Early treatment is recommended, with a multidisciplinary approach to reduce the impact of sequelae on the lives of MS patients or their families.

CONCLUSIONS:

Early treatment is recommended, with a multidisciplinary approach to diminish the impact of sequelae on the lives of MS patients or their families.

• Authors: Marisabel Magnifico, Diana Cassi, Mauro Gandolfini, Andrea Toffoli, Piero A Zecca, Alberto Di Blasio
• Journal: Minerva stomatologica (Minerva Stomatol) Vol. 67 Issue 4 Pg. 165-171 (Aug 2018) ISSN: 1827-174X [Electronic] Italy
• PMID: 29527867 (Publication Type: Journal Article, Observational Study)

Topics

• Adolescent
• Adult
• Cephalometry
• Child
• Child, Preschool
• Cleft Lip
• Cleft Palate
• Diagnosis, Oral
• Female
• Humans
• Infant
• Limb Deformities, Congenital
• Male
• Malocclusion, Angle Class II (etiology, therapy)
• Micrognathism (etiology, therapy)
• Middle Aged
• Mobius Syndrome (embryology, genetics, pathology)
• Orthodontics, Corrective (methods)
• Patient Compliance
• Phenotype
• Strabismus
• Young Adult