Abstract | BACKGROUND: OBJECTIVE: METHODS: A 6-month, open study was conducted in 15 subjects with metatarsalgia because of regularly wearing high-heeled shoes. Hyaluronic acid (20 mg/mL) with lidocaine hydrochloride (3 mg/mL) was injected under the metatarsal heads at baseline. Pain (on a 0-10 scale) under the metatarsal heads when walking in high heels was recorded in a weekly subject diary. RESULTS: At 6 months after injections, 5 subjects (33.3%) reported no metatarsalgia pain. For subjects with pain, they were able to wear high heels for significantly longer than before the injections (7.2 hours at 6 months vs 3.4 hours at baseline). Significant improvements from baseline were observed at Month 6 for time to onset of pain (3.5 hours longer), time between onset of pain and intolerable pain (1.9 hours longer), and pain sensation (-2.2 grades at onset and -3.8 grades at shoe removal). No adverse events were reported. CONCLUSION: Injection of hyaluronic acid filler to the forefeet provided a significant effective, long-lasting, and well-tolerated improvement in metatarsalgia because of wearing high-heeled shoes.
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Authors | Jean Paul Foumenteze, Helen Simpson, Nabil Kerrouche |
Journal | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
(Dermatol Surg)
Vol. 44
Issue 7
Pg. 994-1001
(07 2018)
ISSN: 1524-4725 [Electronic] United States |
PMID | 29360658
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Dermal Fillers
- Viscosupplements
- Hyaluronic Acid
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Topics |
- Adult
- Dermal Fillers
(therapeutic use)
- Female
- Follow-Up Studies
- Forefoot, Human
- France
- Humans
- Hyaluronic Acid
(therapeutic use)
- Injections
- Metatarsalgia
(diagnosis, etiology, therapy)
- Middle Aged
- Pain Measurement
- Shoes
(adverse effects)
- Time Factors
- Treatment Outcome
- Viscosupplements
(therapeutic use)
- Walking
- Weight-Bearing
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