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Hyaluronic Acid Filler Injections Under the Metatarsal Heads Provide a Significant and Long-Lasting Improvement in Metatarsalgia From Wearing High-Heeled Shoes.

AbstractBACKGROUND:
Metatarsalgia is a common overuse injury that may be caused by wearing high-heeled shoes.
OBJECTIVE:
To evaluate the decrease in metatarsalgia using a hyaluronic acid dermal filler.
METHODS:
A 6-month, open study was conducted in 15 subjects with metatarsalgia because of regularly wearing high-heeled shoes. Hyaluronic acid (20 mg/mL) with lidocaine hydrochloride (3 mg/mL) was injected under the metatarsal heads at baseline. Pain (on a 0-10 scale) under the metatarsal heads when walking in high heels was recorded in a weekly subject diary.
RESULTS:
At 6 months after injections, 5 subjects (33.3%) reported no metatarsalgia pain. For subjects with pain, they were able to wear high heels for significantly longer than before the injections (7.2 hours at 6 months vs 3.4 hours at baseline). Significant improvements from baseline were observed at Month 6 for time to onset of pain (3.5 hours longer), time between onset of pain and intolerable pain (1.9 hours longer), and pain sensation (-2.2 grades at onset and -3.8 grades at shoe removal). No adverse events were reported.
CONCLUSION:
Injection of hyaluronic acid filler to the forefeet provided a significant effective, long-lasting, and well-tolerated improvement in metatarsalgia because of wearing high-heeled shoes.
AuthorsJean Paul Foumenteze, Helen Simpson, Nabil Kerrouche
JournalDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 44 Issue 7 Pg. 994-1001 (07 2018) ISSN: 1524-4725 [Electronic] United States
PMID29360658 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Dermal Fillers
  • Viscosupplements
  • Hyaluronic Acid
Topics
  • Adult
  • Dermal Fillers (therapeutic use)
  • Female
  • Follow-Up Studies
  • Forefoot, Human
  • France
  • Humans
  • Hyaluronic Acid (therapeutic use)
  • Injections
  • Metatarsalgia (diagnosis, etiology, therapy)
  • Middle Aged
  • Pain Measurement
  • Shoes (adverse effects)
  • Time Factors
  • Treatment Outcome
  • Viscosupplements (therapeutic use)
  • Walking
  • Weight-Bearing

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