Centrifugal micropipette-tip with pressure signal readout for portable quantitative detection of myoglobin.

Abstract

This paper describes a centrifugal micropipette-tip method for ELISA sample processing combined with a pressure meter for portable quantitative detection of acute myocardial infarction (AMI) biomarker myoglobin (Myo). The method enables sensitive and reliable quantification of Myo in 35 minutes. With the advantages of simplicity, speed, user friendliness, low cost, and small sample consumption, centrifugal micropipette-tip ELISA shows great potential for quantitative POC diagnostics for AMI.

• Authors: Yanling Song, Yuan An, Weizhi Liu, Wanfu Hou, Xingrui Li, Bingqian Lin, Zhi Zhu, Shengxiang Ge, Huang-Hao Yang, Chaoyong Yang
• Journal: Chemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 53 Issue 86 Pg. 11774-11777 (Aug 22 2017) ISSN: 1364-548X [Electronic] England
• PMID: 29034393 (Publication Type: Journal Article)

Chemical References

• Biomarkers
• Myoglobin

Topics

• Biomarkers (analysis)
• Centrifugation (instrumentation, methods)
• Enzyme-Linked Immunosorbent Assay (instrumentation, methods)
• Humans
• Myocardial Infarction (diagnosis)
• Myoglobin (analysis)
• Pressure