A Retrospective Study, an Initial Lesion of Primary Malignant Melanoma of the Esophagus Revealed by Endoscopy.

Abstract

A 66-year-old man presented to his previous physician with epigastric discomfort in 2014. He was then referred to our hospital due to suspected primary malignant melanoma of the esophagus (PMME). A biopsy showed atypical cells containing melanin granules. A diagnosis of PMME was thus made. We investigated the endoscopic findings of the previous physician, which revealed a black point-like pigmentation at the same site since 2009. In 2010, black pigmentation was also observed at the same site. Although esophageal melanosis was suspected, no biopsy was performed. This case demonstrates the process by which esophageal melanomas develop into malignant melanomas.

• Authors: Sho Fukuda, Hirotaka Ito, Reina Ohba, Yuichirou Sato, Motoki Ohyauchi, Takehiko Igarashi, Nobuya Obana, Katsunori Iijima
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 56 Issue 16 Pg. 2133-2137 (Aug 15 2017) ISSN: 1349-7235 [Electronic] Japan
• PMID: 28781311 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Biopsy (methods)
• Early Detection of Cancer (methods)
• Endoscopy (methods)
• Esophageal Neoplasms (diagnosis, diagnostic imaging, pathology)
• Humans
• Male
• Melanoma (diagnosis, pathology)
• Melanosis (diagnosis, pathology)
• Retrospective Studies
• Skin Neoplasms (diagnosis, pathology)
• Melanoma, Cutaneous Malignant