Abstract | BACKGROUND:
Lipid emulsion has been reported to be effective for the treatment of local anaesthetic overdoses in rats, dogs and man. OBJECTIVES: To describe the successful treatment of cardiovascular lidocaine toxicity in a foal with intravenous lipid administration. STUDY DESIGN: Observational study: case report. METHODS: An 8-month-old Arabian cross foal was anaesthetised for removal of the right alar fold and nasal plate. Anaesthesia was maintained with isoflurane in oxygen and lidocaine administered with a loading dose followed by a continuous rate infusion (CRI). The anaesthetic period was uneventful and 30 min before expected termination of the procedure lidocaine infusion was stopped. A sudden drop in mean arterial blood pressure was then observed. The ECG signal was lost, the end tidal CO2 tension dropped from 40 to 10 mmHg, corneal reflex was absent and asystole diagnosed. Cardiopulmonary resuscitation manoeuvres were immediately initiated, but epinephrine and atropine were unsuccessfully administered. Lipid emulsion was administered and the heart rate and arterial blood pressure gradually returned to normal. RESULTS: The foal recovered consciousness 3 h later, regained its sternal position, was responsive and 20 h later was able to stand up alone. MAIN LIMITATIONS: It will be necessary to evaluate a greater number of cases to determine the effectiveness of lipids in foals intoxicated with lidocaine. CONCLUSION:
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Authors | V Vieitez, I Á Gómez de Segura, M Martin-Cuervo, L A Gracia, L J Ezquerra |
Journal | Equine veterinary journal
(Equine Vet J)
Vol. 49
Issue 6
Pg. 767-769
(Nov 2017)
ISSN: 2042-3306 [Electronic] United States |
PMID | 28502090
(Publication Type: Case Reports)
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Copyright | © 2017 EVJ Ltd. |
Chemical References |
- Fat Emulsions, Intravenous
- Lidocaine
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Topics |
- Administration, Intravenous
- Animals
- Fat Emulsions, Intravenous
(therapeutic use)
- Heart Arrest
(chemically induced, drug therapy, veterinary)
- Horse Diseases
(chemically induced, drug therapy)
- Horses
- Lidocaine
(adverse effects)
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