Isoflurane

Subscribe to Selected New Research on Isoflurane

1685 relevant articles (85 outcomes, 188 trials/studies) found for this Drug

Description: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Also Known As:

Ethane, 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro-

Relationship Network

Drug Context: Research Results

Organic Chemicals: 40

1-bromo-1-(difluoromethoxy)-2,2,2-trifluoroethane: 1

Experts

1.	Warltier, David C: 11 articles (05/2007 - 01/2002)
2.	Pagel, Paul S: 10 articles (08/2006 - 01/2002)
3.	Kersten, Judy R: 10 articles (08/2006 - 01/2002)
4.	Krolikowski, John G: 8 articles (05/2006 - 01/2002)
5.	Zuo, Zhiyi: 6 articles (06/2008 - 12/2003)
6.	Bienengraeber, Martin: 5 articles (05/2007 - 10/2005)
7.	Weihrauch, Dorothee: 5 articles (08/2006 - 06/2003)
8.	Kehl, Franz: 5 articles (12/2003 - 01/2002)
9.	Li, Quan: 3 articles (05/2008 - 07/2005)
10.	Yu, Wei-Feng: 3 articles (05/2008 - 07/2005)

Related Diseases

1.	Ischemia 12/01/2007 - "Isoflurane also improved the motor coordination of rats at 1 month after ischemia" 07/01/2006 - "BACKGROUND: Isoflurane provides protection against severe forebrain ischemia in the rat" 05/01/1989 - "Compared with N2O alone, isoflurane (0.5 and 1 MAC) improved neurologic outcome following moderate ischemia (P less than 0.05)" 05/01/2004 - "The natural history of long-term responses to forebrain ischemia requires further study before conclusions can be drawn with respect to the permanence of isoflurane neuroprotection." 05/01/2004 - "CONCLUSIONS: This study found no change in the percent alive CA1 hippocampal neurons as a function of duration of recovery from severe forebrain ischemia in isoflurane anesthetized rats" Get all the results and reference details, order at left...
2.	Brain Ischemia (Cerebral Ischemia) 08/07/2002 - "Three hours of exposure to 1% isoflurane induced rapid and longlasting protection against 60 min transient focal cerebral ischemia induced by filament occlusion of the middle cerebral artery (MCAO)" 06/01/2008 - "Application of isoflurane during reperfusion also improved neurologic outcome after brain ischemia" 12/01/2007 - "CONCLUSIONS: Isoflurane preconditioning improved the long-term neurologic outcome after brain ischemia" 01/01/2007 - "Isoflurane provides long-term protection against focal cerebral ischemia in the rat." 05/01/2004 - "Here, we report that isoflurane preconditioning (2% isoflurane for 30 min at 24 h before brain ischemia) reduced brain infarct sizes and improved neurological deficit scores assessed 6, 24, and 72 h after permanent right middle cerebral arterial occlusion (MCAO) in adult male rats" Get all the results and reference details, order at left...
3.	Hypotension (Low Blood Pressure) 09/01/1986 - "It is concluded that isoflurane is a safe and effective agent for the induction of hypotension in neurosurgical operations." 11/01/2003 - "CONCLUSIONS: Isoflurane resulted in improved neurologic function and reduced histologic damage regardless of the presence or absence of systemic hypotension during the ischemic insult" 11/01/2003 - "This study was designed to determine if isoflurane protection persists in a global insult devoid of hypotension" 05/01/1997 - "The present study demonstrates that isoflurane produces similar effects on systemic blood pressure, regional cerebral blood flow and sympathetic efferent discharge during vasodilator-induced hypotension and without any vasodilator." 10/01/2007 - "Severe (10 min), moderate (8 min), or mild (6 min) forebrain ischaemia was produced by bilateral carotid occlusion combined with hypotension (35 mm Hg) under isoflurane (1.5%) anaesthesia" Get all the results and reference details, order at left...
4.	Anoxia (Hypoxia) 03/01/2008 - "Because a rapid rebound response did not develop, inhalation of NO might be clinically useful in the treatment of hypoxemia in healthy isoflurane-anesthetized horses." 02/10/1987 - "Isoflurane (1.5%) was able to provide a small degree of protection against shorter periods (7 min) of anoxia." 04/01/2000 - "This study examined how a period of global birth anoxia and isoflurane/N2O anaesthesia interact to affect measures of CNS and systemic hypoxia in neonatal rats born by C-section compared with control, vaginally born animals" 01/01/1997 - "This study investigated the ability of isoflurane to protect the liver from hypoxia-reoxygenation injury and the mechanisms of this phenomenon" 03/01/1996 - "In the isoflurane studies, 1 min of mild hypoxia (Iso-1 study: PE'O2 6.2 kPa) and 1 min of moderate hypoxia (Iso-2 study: PE'O2 5.7 kPa) were followed by sudden transition to normoxia during inhalation of 0.1 minimum alveolar concentration (MAC) of isoflurane" Get all the results and reference details, order at left...
5.	Hypothermia 02/01/1992 - "The present study was undertaken to examine the cerebral protective properties attributed to isoflurane and at the same time to compare its protective effects with those of mild hypothermia (temperature reduction by 3 degrees C)" 03/01/2001 - "CONCLUSIONS: Hypothermia decreases the isoflurane requirement in children by 5.1 degrees C." 03/01/2001 - "The effect of hypothermia on isoflurane MAC in children." 03/01/2000 - "The LCBF-to-LCGU ratio increased from 1.4 (conscious controls) to 2.4 (normothermic isoflurane) and 3.6 ml/micromol (mild and moderate hypothermia, P < 0.05)" 09/01/1998 - "During mild hypothermia, isoflurane depressed thermoregulatory vasoconstriction dose-dependently until its concentration reached 0.6-0.7%" Get all the results and reference details, order at left...
306 Diseases and 1685 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Halothane (Fluothane)
2.	Propofol (Diprivan)
3.	sevoflurane (Ultane)
4.	Fentanyl (Sublimaze)
5.	Enflurane (Ethrane)
6.	Thiopental (Pentothal)
7.	Pentobarbital (Nembutal)
8.	Nitrous Oxide (Laughing Gas)
9.	Anesthetics (Anesthetic Agents)
10.	Adenosine Triphosphate (ATP)
448 Drugs and Important Bio-Agents and 1208 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Anesthesia
2.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
3.	Inhalation Anesthesia
4.	General Anesthesia
5.	Intravenous Anesthesia
88 Therapies and Procedures and 543 more articles analyzed in the Research Interface, order at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>