Abstract | INTRODUCTION:
Lactose intolerance is a common disease in pediatrics, and its wrong diagnosis will lead to morbidity. The primary objective of this study was to assess the usefulness of an increased waist circumference during the hydrogen breath test as a predictor of lactose intolerance. The secondary objective was to analyze the impact of body mass index, waist circumference measurement, and age on the abdominal distension of patients with lactose intolerance. POPULATION AND METHODS: A total of 138 subjects aged 3 to 15 years were included. They underwent serial measurements of the waist circumference and hydrogen levels in the breath every 30 minutes over 3 hours during the hydrogen breath test. RESULTS: Out of the entire sample, 35 (25.4%) patients had lactose intolerance. An increase of 0.85 cm in waist circumference compared to the baseline waist circumference results in a sensitivity of 88% and a specificity of 85% to predict lactose intolerance (odds ratio: 42.14, 95% confidence interval: 13.08-135.75, p ≤ 0.001). The body mass index and waist circumference measurement did not affect abdominal distension (p= not significant); however, age modified the time of distension. CONCLUSIONS: A 0.85 cm increase in waist circumference compared to the baseline waist circumference during the hydrogen breath test is a useful parameter for the diagnosis of lactose intolerance in pediatrics. Variations in relation to body mass index and waist circumference did not affect the usefulness of an increased waist circumference, unlike age.
|
Authors | Carlos A Zapata-Castilleja, Fernando F Montes-Tapia, Consuelo Treviño-Garza, María C Martínez-Cobos, Jesús García-Cantú, Vincenzo Arenas-Fabbri, Norma de la O-Escamilla, Manuel de la O-Cavazos |
Journal | Archivos argentinos de pediatria
(Arch Argent Pediatr)
Vol. 115
Issue 2
Pg. 148-154
(04 01 2017)
ISSN: 1668-3501 [Electronic] Argentina |
Vernacular Title | Comparación del incremento del perímetro abdominal con la prueba de hidrógeno espirado como predictor clínico de intolerancia a la lactosa. |
PMID | 28318180
(Publication Type: Comparative Study, Journal Article, Observational Study)
|
Chemical References |
|
Topics |
- Adolescent
- Breath Tests
- Child
- Child, Preschool
- Cross-Sectional Studies
- Female
- Humans
- Hydrogen
(analysis)
- Lactose Intolerance
(diagnosis)
- Male
- Predictive Value of Tests
- Waist Circumference
|