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Hydrogen

The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
Also Known As:
Hydrogen-1; Protium
Networked: 3493 relevant articles (313 outcomes, 521 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Xie, Keliang: 50 articles (09/2022 - 07/2010)
2. Sun, Xuejun: 47 articles (01/2021 - 08/2008)
3. Yu, Yonghao: 46 articles (09/2022 - 07/2010)
4. Chen, Hongguang: 29 articles (09/2022 - 05/2012)
5. Yu, Yang: 25 articles (06/2021 - 01/2012)
6. Wang, Guolin: 22 articles (12/2021 - 07/2010)
7. Zhang, John H: 22 articles (01/2021 - 08/2008)
8. Nakao, Atsunori: 21 articles (10/2021 - 01/2010)
9. Ohta, Shigeo: 20 articles (10/2021 - 09/2007)
10. Ohno, Kinji: 18 articles (03/2022 - 04/2009)

Related Diseases

1. Inflammation (Inflammations)
2. Reperfusion Injury
3. Sepsis (Septicemia)
09/01/2014 - "Compared with the sepsis group, in the hydrogen treatment group, the number of normal pyramidal neurons in the hippocampal CA1 region was markedly increased (67.33 ± 6.89 vs. 42.33 ± 6.02, P<0.01), the apoptotic index was dramatically reduced [(30.00 ± 4.77)% vs. (80.50 ± 6.99)%, P<0.01], the expressions of nucleus and total Nrf2 were significantly increased [nucleus Nrf2 (A value): 5.07 ± 0.35 vs. 3.04 ± 0.34, total Nrf2 (A value): 4.24 ± 0.58 vs. 2.91 ± 0.37, both P<0.01], the activities of SOD and CAT in the hippocampus were significantly increased [SOD (U/mg): 120.96 ± 13.44 vs. 81.16 ± 12.28, CAT (U/mg): 9.11 ± 1.28 vs. 5.64 ± 1.88, both P<0.01], and the levels of MDA and 8-iso-PGF2α were markedly reduced [MDA (nmol/mg): 16.12 ± 1.49 vs. 27.64 ± 1.87, 8-iso-PGF2α (pg/mg): 183.43 ± 13.07 vs. 864.07 ± 49.92, both P<0.01], the escape latency at day 5 to 8 after operation was significantly shortened, and there was no difference in swimming speed, the percentage of time in the target quadrant [(37.06 ± 1.16)% vs. (24.42 ± 1.82)%, P<0.01] and the times of the platform crossing (7.13 ± 0.98 vs. 4.88 ± 0.99, P<0.01) were significantly increased on probe day. "
01/01/2020 - "The acute treatment with molecular hydrogen (H2) exerts important antioxidative, antiapoptotic, and anti-inflammatory effects in sepsis, but little is known about the mechanism itself and the efficacy of chronic H2 inhalation in sepsis treatment. "
06/01/2015 - "Hydrogen gas (H2) is effective for treating sepsis. "
08/01/2021 - "Furthermore, we evaluated the role of mitophagy in the protective effects of hydrogen against cell injury or organ dysfunction in sepsis. "
09/01/2014 - "To investigate the role of nuclear factor erythroid 2-related factor 2 (Nrf2) in the protective effects of hydrogen against cerebral dysfunction in a mouse model of sepsis. "
4. Ischemia
5. Lung Injury

Related Drugs and Biologics

1. Antioxidants
2. Oxygen (Dioxygen)
3. Sodium
4. Proteins (Proteins, Gene)
5. Reactive Oxygen Species (Oxygen Radicals)
6. Lactose
7. Lactulose (Duphalac)
8. Lipopolysaccharides
9. Sulfates (Sulfates, Inorganic)
10. Solutions

Related Therapies and Procedures

1. Therapeutics
2. Electrodes (Electrode)
3. Resuscitation
4. Drug Therapy (Chemotherapy)
5. Oral Administration