Unusual presentation of local anesthetic toxicity.

Abstract

The local anesthetic systemic toxicity can be due to increased blood lignocaine levels or due to increased sensitivity to lignocaine. Several cases of lignocaine-induced central nervous system toxicity have been noted, but none have reported only loss of consciousness without any seizure-like activity. Intravenous lipid emulsion administration for the treatment of local anesthetic systemic toxicity is an emerging topic of discussion, and there are case reports where they had successfully been used. However, majority of them were used in the treatment of cardiovascular manifestations of local anesthetic toxicity. We report a case of a 19-year-old man who had unconsciousness on 2 separate occasions after local lignocaine infiltration to undergo surgery for dental malocclusion and the use of lipid emulsion in its management.

• Authors: Nitin Hayaran, Rashi Sardana, Hamse Nandinie, Aruna Jain
• Journal: Journal of clinical anesthesia (J Clin Anesth) Vol. 36 Pg. 36-38 (Feb 2017) ISSN: 1873-4529 [Electronic] United States
• PMID: 28183570 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2016 Elsevier Inc. All rights reserved.

Chemical References

• Anesthetics, Local
• Emulsions
• Phospholipids
• soybean oil, phospholipid emulsion
• Soybean Oil
• Lidocaine

Topics

• Anesthetics, Local (adverse effects)
• Emulsions (therapeutic use)
• Humans
• Lidocaine (adverse effects)
• Male
• Malocclusion (surgery)
• Phospholipids (therapeutic use)
• Postoperative Complications (therapy)
• Soybean Oil (therapeutic use)
• Unconsciousness (chemically induced, therapy)
• Young Adult