Abstract | OBJECTIVES: METHODS: Among 137 patients who received chemotherapy for CLM and underwent gadoxetic acid-enhanced MRI and DWI between 2010 and 2012, 43 patients with 168 DLMs and 48 RTCLMs were included. The cumulative in situ recurrence rate of DLM and progression rate of RTCLM and their predictive factors were evaluated. RESULTS: A total of 150 DLMs and 26 RTCLMs were followed up without additional treatment. At 1 and 2 years, respectively, the cumulative in situ recurrence rates for DLM were 10.9 % and 15.7 % and the cumulative progression rates for RTCLM were 27.2 % and 33.2 %. The in situ recurrence rate at 2 years was 4.9 % for the DLM group that did not show reticular hypointensity of liver parenchyma on hepatobiliary phase. CONCLUSIONS: KEY POINTS: • DLMs on gadoxetic acid-enhanced MRI and DWI showed low recurrence rates. • If there is sinusoidal obstruction syndrome, evaluation of DLM needs special care. • The progression rate for residual tiny CLMs was 33.2 % at 2 years.
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Authors | Seung Soo Kim, Kyoung Doo Song, Young Kon Kim, Hee Cheol Kim, Jung Wook Huh, Young Suk Park, Joon Oh Park, Seung Tae Kim |
Journal | European radiology
(Eur Radiol)
Vol. 27
Issue 7
Pg. 3088-3096
(Jul 2017)
ISSN: 1432-1084 [Electronic] Germany |
PMID | 27815722
(Publication Type: Journal Article)
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Chemical References |
- Antineoplastic Agents
- Contrast Media
- gadolinium ethoxybenzyl DTPA
- Gadolinium DTPA
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Topics |
- Antineoplastic Agents
(therapeutic use)
- Colorectal Neoplasms
(diagnosis, drug therapy, secondary)
- Contrast Media
(pharmacology)
- Diffusion Magnetic Resonance Imaging
(methods)
- Disease Progression
- Female
- Follow-Up Studies
- Gadolinium DTPA
(pharmacology)
- Humans
- Liver Neoplasms
(drug therapy, pathology)
- Magnetic Resonance Imaging
(methods)
- Male
- Middle Aged
- Neoplasm Metastasis
- Neoplasm Staging
(methods)
- Neoplasm, Residual
- Reproducibility of Results
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