Breast cancer is a malignant disease to treat among female worldwide due to its high capability to metastasize and mutate. Epithelial-mesenchymal transition is one of the essential processes involved in the metastatic capacity of
breast cancer. In the recent time, the studies demonstrate that
microRNAs, a kind of
small non-coding RNA molecules, could be served as negative regulators in
breast cancer, regulating cell cycle, drug resistance, and the process of
metastasis in
cancer development. With the assistance of
microRNA profiling, the study concentrating on the regulatory function of
miRNAs in
breast cancer could be investigated more effectively and efficiently. More recent studies demonstrate that
miRNAs have an important role to play in the EMT process of
breast cancer to modulate
metastasis. This small essay is on the purpose of demonstrating the significance and detection of
miRNAs in
breast cancer EMT process as oncogenes and
tumor suppress genes through
miRNA profiling according to the reports mainly in the recent 5 years, providing the evidence of efficient target
therapy and effective pro-diagnosis focusing on
miRNAs expression of
breast cancer patients.