Abstract | BACKGROUND: METHODS: Ninety patients of either sex undergoing elective spine surgery and requiring urinary catheterization were randomly assigned into three groups to receive oral solifenacin 5 mg (Group S), darifenacin 7.5 mg (Group D) and placebo (Group C) 1 hour prior to induction of anesthesia. Anesthesia technique was identical in all the groups. Catheter-related bladder discomfort (CRBD) was evaluated in 4-point scale (1 = no discomfort, 2 = mild discomfort, 3 = moderate discomfort, 4 = severe discomfort), on arrival (0 hour) and at 1, 2, and 6 hours postoperatively. Patients were provided patient-controlled analgesia with fentanyl for postoperative pain relief. RESULTS: There were no significant differences in demographic profile and fentanyl requirements (P>0.05). The prevalence and severity of CRBD were significantly less in the group D and group S compared with the group C at all time intervals (P<0.05). CONCLUSIONS:
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Authors | Vinit K Srivastava, Rakesh Nigam, Sanjay Agrawal, Sanjay Kumar, Sonal Rambhad, Jayant Kanaskar |
Journal | Minerva anestesiologica
(Minerva Anestesiol)
Vol. 82
Issue 8
Pg. 867-73
(08 2016)
ISSN: 1827-1596 [Electronic] Italy |
PMID | 27607187
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics, Opioid
- Benzofurans
- Pyrrolidines
- Urological Agents
- darifenacin
- Solifenacin Succinate
- Fentanyl
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Topics |
- Analgesics, Opioid
- Benzofurans
(administration & dosage)
- Double-Blind Method
- Female
- Fentanyl
- Humans
- Intraoperative Period
- Male
- Pain, Postoperative
- Prospective Studies
- Pyrrolidines
(administration & dosage)
- Solifenacin Succinate
(administration & dosage)
- Treatment Outcome
- Urinary Bladder
- Urinary Catheterization
(adverse effects)
- Urological Agents
(administration & dosage)
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