Thrombolytic treatment in a patient with antiphospholipid syndrome : APS developing renal infarction.

Abstract

Antiphospholipid syndrome (APS), a leading entity in acquired thrombophilia, is characterized by recurrent thrombosis, morbidity in pregnancy and presence of antiphospholipid antibodies (APA). Although the etiopathogenesis is unclear, APA against negatively charged phospholipids and phospholipid-protein complexes are held responsible for the clinical picture. In case of acute thrombosis due to APS, thrombolytic therapy is not a commonly administered treatment option. Here, we present a case with acute thrombosis in the left renal artery showing partial response to thrombolytic therapy.

• Authors: Y Ugan, A Dogru, M Sahin, S E Tunc
• Journal: Zeitschrift fur Rheumatologie (Z Rheumatol) Vol. 75 Issue 8 Pg. 838-841 (Oct 2016) ISSN: 1435-1250 [Electronic] Germany
• Vernacular Title: Thrombolysetherapie bei einem Patienten mit Antiphospholipidsyndrom : Durch APS entwickelter Niereninfarkt.
• PMID: 27418058 (Publication Type: Case Reports, Journal Article)

Chemical References

• Fibrinolytic Agents

Topics

• Adult
• Antiphospholipid Syndrome (complications, diagnosis, drug therapy)
• Diagnosis, Differential
• Female
• Fibrinolytic Agents (administration & dosage)
• Humans
• Infarction (diagnosis, etiology, prevention & control)
• Kidney (blood supply)
• Treatment Outcome