Acquired methemoglobinemia in infants.

Abstract

OBJECTIVE:

This study aimed to determine the etiologic factors of acquired methemoglobinemia in infants younger than three months in our region.

METHODS:

This study was carried out retrospectively in infants with methemoglobinemia admitted to Karadeniz Technical University, Pediatric Clinic, during the period 2000-2009. Infants with methemoglobinemia were identified according to the medical records or ICD-10 code.

RESULTS:

Nine infants with acquired methemoglobinemia (8 male, 1 female) were included in the study. Seven cases were associated with the use of prilocaine for circumcision, one case with the use of prilocaine-lidocaine for local pain therapy, and one case with neonatal sepsis caused by Staphylococcus aureus.

CONCLUSION:

Prilocaine should not be used in infants less than three months of age because of the risk of methemoglobinemia. Ascorbic acid is an effective therapy if methylene blue is not obtained. It should not be forgotten that sepsis caused by S. aureus may cause methemoglobinemia in infants.

• Authors: Mehmet Mutlu, Erol Erduran, Yakup Aslan
• Journal: Turkish journal of haematology : official journal of Turkish Society of Haematology (Turk J Haematol) Vol. 28 Issue 2 Pg. 131-4 (Jun 05 2011) ISSN: 1300-7777 [Print] Turkey
• Vernacular Title: Süt çocuklarında edinsel methemoglobinemi.
• PMID: 27264127 (Publication Type: Journal Article)