[Combination surgery for wet age-related macular degeneration and chronic peripheral uveitis].

Abstract

AIM:

To develop a combination surgery for wet age-related macular degeneration and concurrent chronic peripheral uveitis that would include intravitreal injection of Lucentis and cryocerclage of the peripheral retina.

MATERIAL AND METHODS:

A total of 75 patients were examined and divided into 2 groups: the main group (37 patients) and the controls (38 patients). Patients from the main group underwent the new combination surgery, while the controls received intravitreal Lucentis alone (peripheral uveitis was managed therapeutically).

RESULTS:

It has been found that the new combination method provides a significant and stable improvement in visual acuity (by a factor of 10) and a decrease in the area of central scotoma (by a factor of 2.95) in the postoperative period. The period needed for recovery in the central retinal thickness is also 1.6 times shorter.

CONCLUSION:

The new combination surgery for wet age-related macular degeneration and concurrent chronic peripheral uveitis provides rapid reduction of inflammation in the extreme periphery of the fundus and a 1.5 times faster (as compared to traditional methods) primary restoration of topographic anatomy of the retina in the macular region.

• Authors: I V Zapuskalov, O I Krivosheina, Yu I Khoroshikh
• Journal: Vestnik oftalmologii (Vestn Oftalmol) 2016 Mar-Apr Vol. 132 Issue 2 Pg. 80-84 ISSN: 0042-465X [Print] Russia (Federation)
• PMID: 27213803 (Publication Type: English Abstract, Journal Article)

Chemical References

• Angiogenesis Inhibitors
• Ranibizumab

Topics

• Aged
• Angiogenesis Inhibitors (administration & dosage)
• Chronic Disease
• Combined Modality Therapy
• Diagnostic Techniques, Ophthalmological
• Female
• Humans
• Intravitreal Injections
• Male
• Middle Aged
• Ophthalmologic Surgical Procedures (methods)
• Ranibizumab (administration & dosage)
• Scotoma (diagnosis, etiology, therapy)
• Treatment Outcome
• Uveitis (complications, diagnosis, therapy)
• Visual Acuity
• Wet Macular Degeneration (complications, diagnosis, drug therapy, physiopathology, surgery)