[Roles of Inflammatory Reaction and Cytokines in Chronic Postsurgical Pain].

Abstract

Chronic postsurgical pain (CPSP) is characterized by high incidence,prolonged duration,multiple risk factors,and complicated pathogenesis. It seriously impairs patients' quality of life,especially after thoracotomy. Perioperative nerve injury is a major cause of CPSP. Meanwhile,the excessive neuroinflammation and inflammatory cytokines caused by surgery also accelerate the formation of CPSP. This review aims to provide an overview of the recent advances in the roles of inflammatory reaction and cytokines in the development of CPSP.

• Authors: Ling Lan, Le Shen, Yu-guang Huang
• Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae (Zhongguo Yi Xue Ke Xue Yuan Xue Bao) Vol. 37 Issue 6 Pg. 741-5 (Dec 2015) ISSN: 1000-503X [Print] China
• PMID: 26725399 (Publication Type: Journal Article)

Chemical References

• Cytokines

Topics

• Chronic Pain
• Cytokines
• Humans
• Incidence
• Inflammation
• Pain, Postoperative
• Quality of Life
• Risk Factors