Abstract | BACKGROUND: METHODS: In a descriptive study, gene expression profile of CCR1, CCR6, CCR7, CCR9, CXCR1, and CXCR4 in human esophageal cancer cell line (KYSE-30) and human breast cancer cell line (MCF7) were analyzed using real-time PCR and their results were compared accordingly. RESULTS: We demonstrated for the first time the expression of CCR1, CCR6, CCR7, CCR9, CXCR1, and CXCR4 at transcriptional level in human esophageal cancer cell line. The expression of CCR1, CCR7 and CXCR4 were lower in esophageal compared with breast cancer cells, although without significant difference. CCR9 was highly expressed in esophageal cancer cells as compared to the breast cancer cells (P < 0.05). Similarly, the expression of CCR6 and CXCR1 were higher, although without significant difference. CONCLUSION:
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Authors | Mohammad Amir Mishan, Asieh Heirani-Tabasi, Neda Mokhberian, Malihe Hassanzade, Hamid Kalalian Moghaddam, Ahmad Reza Bahrami, Naghmeh Ahmadiankia |
Journal | Iranian journal of public health
(Iran J Public Health)
Vol. 44
Issue 10
Pg. 1353-8
(Oct 2015)
ISSN: 2251-6085 [Print] Iran |
PMID | 26576348
(Publication Type: Journal Article)
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