Abstract |
The alexidine mouthrinse used in this study (CP-101) is effective in reducing plaque. There was a reduction in gingivitis after 6-months use but not at a statistically significant level. An extrinsic brown stain occurred at a significant level on the teeth of participants using the active mouthrinse. Blood and urine laboratory results indicated that alexidine can be safely used over a 6-month period.
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Authors | H C Carlson, K Porter, T H Alms |
Journal | Journal of periodontology
(J Periodontol)
Vol. 48
Issue 4
Pg. 216-8
(Apr 1977)
ISSN: 0022-3492 [Print] United States |
PMID | 265389
(Publication Type: Journal Article)
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Chemical References |
- Biguanides
- Mouthwashes
- Placebos
- alexidine
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Topics |
- Adolescent
- Adult
- Aged
- Biguanides
(adverse effects, therapeutic use)
- Color
- Dental Plaque
(prevention & control)
- Gingivitis
(prevention & control)
- Humans
- Middle Aged
- Mouthwashes
(adverse effects, therapeutic use)
- Placebos
- Tongue Diseases
(chemically induced)
- Tooth Discoloration
(chemically induced)
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