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The effect of an alexidine mouthwash on dental plaque and gingivitis.

Abstract
The alexidine mouthrinse used in this study (CP-101) is effective in reducing plaque. There was a reduction in gingivitis after 6-months use but not at a statistically significant level. An extrinsic brown stain occurred at a significant level on the teeth of participants using the active mouthrinse. Blood and urine laboratory results indicated that alexidine can be safely used over a 6-month period.
AuthorsH C Carlson, K Porter, T H Alms
JournalJournal of periodontology (J Periodontol) Vol. 48 Issue 4 Pg. 216-8 (Apr 1977) ISSN: 0022-3492 [Print] United States
PMID265389 (Publication Type: Journal Article)
Chemical References
  • Biguanides
  • Mouthwashes
  • Placebos
  • alexidine
Topics
  • Adolescent
  • Adult
  • Aged
  • Biguanides (adverse effects, therapeutic use)
  • Color
  • Dental Plaque (prevention & control)
  • Gingivitis (prevention & control)
  • Humans
  • Middle Aged
  • Mouthwashes (adverse effects, therapeutic use)
  • Placebos
  • Tongue Diseases (chemically induced)
  • Tooth Discoloration (chemically induced)

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