[Effect and safety of GreenLight HPS 120-W laser vaporization of the prostate for different benign prostatic hyperplasia populations].

Abstract

OBJECTIVE:

To evaluated the safety and effect of the 120-W GreenLight HPS laser photoselective vaporization of the prostate (PVP) in different BPH populations.

METHODS:

This study included 174 BPH patients treated by PVP using 120-W Green-Light HPS laser. According to the prostate volume (PV) ( < 80 or ≥ 80 ml), history of 5-alpha reductase inhibitor (5-ARI) medication, and history of acute urinary retention (AUR), we divided the patients into a PV < 80 ml, a PV ≥ 80 ml, a 5-ARI, a no 5-ARI; an AUR, and a no AUR group. We collected the baseline, perioperative, and follow-up data about the patients, and compared them among different groups.

RESULTS:

The patients were aged 69.4 ± 7.7 years, of whom PVP was successfully performed for 136 and PVP was intraoperatively converted to transurethral resection of the prostate (TURP) in the other 38, with a mean operation time of (49.4 ± 16.3) min. The preoperative PV averaged (67.9 ± 29.8) ml. There was no intraoperative blood transfusion, transurethral resection syndrome, or capsule perforation. Bladder neck contracture occurred in 2 cases and urethral stricture developed in another 2 postoperatively. All the patients showed a significant improvement in the prostatic function parameters and no significant differences were observed between the PV < 80 ml and PV ≥ 80 ml, 5-ARI and no 5-ARI, or AUR and no AUR groups.

CONCLUSION:

PVP with 120-W GreenLight HPS laser is safe and efficient for the treatment of BPH and the its effect is not influenced by the prostate volume, history of 5-ARI medication, or history of AUR. However, preoperative urinary catheterization may increase the difficulty of surgery and the risk of conversion to TURP.

• Authors: Kun Fang, Bo Yang, Rui Qu, Qiang Dong
• Journal: Zhonghua nan ke xue = National journal of andrology (Zhonghua Nan Ke Xue) Vol. 21 Issue 7 Pg. 619-25 (Jul 2015) ISSN: 1009-3591 [Print] China
• PMID: 26333224 (Publication Type: Journal Article)

Chemical References

• 5-alpha Reductase Inhibitors

Topics

• 5-alpha Reductase Inhibitors (therapeutic use)
• Aged
• Humans
• Laser Therapy (adverse effects, methods)
• Male
• Operative Time
• Organ Size
• Prostate (pathology, surgery)
• Prostatic Hyperplasia (pathology, surgery)
• Transurethral Resection of Prostate
• Treatment Outcome
• Urethral Stricture (etiology)
• Urinary Bladder
• Urinary Retention