[A Patient Who Underwent Surgery after CR to Chemotherapy for Scirrhous Gastric Cancer Suspected because of Lymphangitis Carcinomatosa].

Abstract

A 58-year-old woman was diagnosed with scirrhous gastric cancer suspected because of lymphangitis carcinomatosa. She was treated with 10 courses of S-1+CDDP chemotherapy. After 3 years and 6 months, CR was obtained and she underwent curative total gastrectomy with D2 lymph node dissection plus resection of the spleen and transverse colon. The pathological results of the resected specimen were tub2>por, pT1a, N1 (No.7), M0, CY0, P0, and HER2 (3+). After surgical treatment, supraclavicular lymph node metastasis occurred, and the patient underwent trastuzumab+capecitabine therapy, which resulted in CR for 1 year and 6 months. Thus, for unresectable scirrhous gastric cancer, multidisciplinary therapy such as longterm chemotherapy including trastuzumab and surgery is useful.

• Authors: Kohei Nishiki, Yumiko Tanaka, Shunsuke Sogabe, Mitsuru Iwama, Tomoki Makino, Osamu Shiraishi, Atsushi Yasuda, Masayuki Shinkai, Motohiro Imano, Haruhiko Imamoto, Hiroshi Furukawa, Takushi Yasuda
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 42 Issue 6 Pg. 739-42 (Jun 2015) ISSN: 0385-0684 [Print] Japan
• PMID: 26199248 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adenocarcinoma, Scirrhous (drug therapy, surgery)
• Antineoplastic Agents (therapeutic use)
• Female
• Gastrectomy
• Humans
• Lymphangitis (etiology)
• Lymphatic Metastasis
• Middle Aged
• Neoadjuvant Therapy
• Recurrence
• Stomach Neoplasms (drug therapy, pathology, surgery)