A 47-year-old Japanese man was diagnosed with
prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical
prostatectomy after
androgen deprivation
therapy (ADT) in June 1995. Nine years after operation, he was diagnosed with local recurrence of
prostate cancer and he received postoperative external beam
radiation therapy (EBRT) (70 Gy). By May 2008, the PSA dropped to 0.33 ng/mL, and a CT scan showed that the mass had disappeared. On April 2012, the PSA once again rose to 3.1 ng/mL. CT scan and MRI revealed a mass in the prostatic bed. We diagnosed local recurrence of
prostate cancer. We underwent salvage low-dose
brachytherapy after obtaining informed consent. The prescribed dose of the salvage
brachytherapy was 145 Gy to control the
tumor considering the
hormone resistant
prostatic cancer and high-risk feature. PSA level rapidly decreased to 0.66 ng/mL by 6 months after seed implantation. No adverse events were seen during the follow-up period.