Abstract | BACKGROUND: METHODS: In this randomized, placebo-controlled trial, we enrolled 110 children (5 months to 6 years of age), who were scheduled for cleft lip surgery, and randomized them to the following two groups: Group S and Group B, where 1.5 ml saline (Group S) or 1.5 ml 0.25% bupivacaine (Group B) were administered in the infraorbital foramen. Emergence behavior was assessed in the postanesthesia care unit using the Pediatric Anesthesia Emergence Delirium (PAED) scale and a 5-point scale described by Cole. Pain was evaluated using the Children and Infants Postoperative Pain Scale (CHIPPS). RESULTS: One-hundred children (n = 50 per group) completed the study. The endtidal concentration of sevoflurane in Group B was lower than that in Group S. The incidence of EA was 16% in Group B and 42% in Group S (P = 0.008). The PAED scale score in Group B (mean [95% CI] 9 [8-12]) was lower than that in Group S (11.5 [9.8-15]). The duration of EA in Group B was shorter than that in Group S. CHIPPS score in postanesthetic care unit were lower in Group B (mean [95% CI] 3 [2-3.3]) compared with that in Group S (5 [4-6]). CONCLUSION: In children undergoing cleft lip repair surgery, infraorbital nerve block at the beginning of surgery significantly decreased the incidence of EA and the duration of EA, and provided satisfactory postoperative analgesia without delaying the time to extubation with sevoflurane anesthesia.
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Authors | Hong Wang, Gang Liu, Wei Fu, Shi-tong Li |
Journal | Paediatric anaesthesia
(Paediatr Anaesth)
Vol. 25
Issue 9
Pg. 906-10
(Sep 2015)
ISSN: 1460-9592 [Electronic] France |
PMID | 26095194
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | © 2015 John Wiley & Sons Ltd. |
Chemical References |
- Anesthetics, Inhalation
- Methyl Ethers
- Sevoflurane
- Sodium Chloride
- Bupivacaine
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Topics |
- Anesthesia Recovery Period
- Anesthesia, General
- Anesthesia, Local
- Anesthetics, Inhalation
- Bupivacaine
- Child
- Child, Preschool
- Cleft Lip
(surgery)
- Female
- Humans
- Infant
- Male
- Methyl Ethers
- Nerve Block
(adverse effects)
- Orbit
(innervation)
- Pain, Postoperative
(complications)
- Prospective Studies
- Psychomotor Agitation
(etiology)
- Sevoflurane
- Sodium Chloride
(administration & dosage)
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