Abstract | OBJECTIVE: METHODS:
Bleeding and thromboembolic events during the periprocedural period were evaluated in 363 consecutive patients who underwent CA for AF at Nagoya University Hospital, and received uninterrupted dabigatran (n=173) or uninterrupted warfarin (n=190) for periprocedural anticoagulation. RESULTS: A total of 27 (7%) patients experienced either bleeding or thromboembolic complications. Major bleeding complications occurred in 2 (1%) patients in the dabigatran group (DG) and 2 (1%) patients in the warfarin group (WG). Eight (5%) patients in the DG and 9 (5%) patients in the WG experienced groin hematoma, a type of minor bleeding complication. Meanwhile, no patient in the DG and 1 (1%) in the WG developed cerebral ischemic stroke. Overall, there was no significant difference between the groups for any category. The activated partial thromboplastin time (APTT) independently predicted periprocedural complications in the DG. CONCLUSION:
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Authors | Tomoyuki Nagao, Yasuya Inden, Masayuki Shimano, Masaya Fujita, Satoshi Yanagisawa, Hiroyuki Kato, Shinji Ishikawa, Aya Miyoshi, Satoshi Okumura, Shiou Ohguchi, Toshihiko Yamamoto, Naoki Yoshida, Makoto Hirai, Toyoaki Murohara |
Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 54
Issue 10
Pg. 1167-73
( 2015)
ISSN: 1349-7235 [Electronic] Japan |
PMID | 25986252
(Publication Type: Journal Article)
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Chemical References |
- Anticoagulants
- Benzimidazoles
- beta-Alanine
- Warfarin
- Dabigatran
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Topics |
- Aged
- Anticoagulants
(administration & dosage)
- Atrial Fibrillation
(drug therapy, therapy)
- Benzimidazoles
(administration & dosage)
- Catheter Ablation
(adverse effects, methods)
- Dabigatran
- Female
- Hemorrhage
(etiology, prevention & control)
- Humans
- Male
- Middle Aged
- Treatment Outcome
- Warfarin
(administration & dosage)
- beta-Alanine
(administration & dosage, analogs & derivatives)
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