A case of atrial tachycardia treated with ivabradine as bridge to ablation.

Abstract

Ivabradine is indicated in cardiac failure and ischemia to reduce sinus rate by inhibition of the pacemaker I(f) current in sinoatrial node. We report a case of an 18-year-old woman with left atrial tachyarrhythmia resistant to several antiarrhythmic drugs and to electric cardioversion who responded only to ivabradine, which significantly reduced heart rate without abolishing the arrhythmia itself. An ectopic focus in the ostium of left pulmonary veins was found and the patient was successfully ablated. We suggest that ivabradine might be therefore useful in the treatment of supraventricular tachyarrhythmias due to an enhanced automaticity.

• Authors: Ester Meles, Claudio Carbone, Stefano Maggiolini, Paolo Moretti, Caterina C DE Carlini, Gaetano Gentile, Tomaso Gnecchi-Ruscone
• Journal: Journal of cardiovascular electrophysiology (J Cardiovasc Electrophysiol) Vol. 26 Issue 5 Pg. 565-8 (May 2015) ISSN: 1540-8167 [Electronic] United States
• PMID: 25656911 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2015 Wiley Periodicals, Inc.

Chemical References

• Anti-Arrhythmia Agents
• Benzazepines
• Ivabradine

Topics

• Adolescent
• Anti-Arrhythmia Agents (therapeutic use)
• Benzazepines (therapeutic use)
• Catheter Ablation
• Electrocardiography
• Electrophysiologic Techniques, Cardiac
• Female
• Heart Rate (drug effects)
• Humans
• Ivabradine
• Pulmonary Veins (drug effects, physiopathology, surgery)
• Tachycardia, Ectopic Atrial (diagnosis, drug therapy, physiopathology, surgery)
• Treatment Outcome