Abstract | INTRODUCTION: PRESENTATION OF CASE: We present the case of an 86-year-old man with chronic kidney disease (CKD) treated with dialysis who was admitted with back pain. He was prescribed and took pravastatin for almost 3 years to treat hyperlipidemia. He received hemodialysis therapy 7 times prior to presentation. Laboratory values included a serum creatine concentration of 6.6mg/dl and a creatinine phosphokinase (CPK) concentration of 2350IU/L. An abdominal computed tomography scan showed swollen muscles with reduced muscle density and air density in the multifidus muscle. Two days after admission, he had large, tender ecchymotic lesions and purpuric progressive skin necrosis over the back, abdomen, and upper and lower extremities. The patient died 6 days after the initial admission due to disseminated intravascular coagulation ( DIC). Based on these findings and the clinical history, a diagnosis of pravastatin-induced rhabdomyolysis and purpura fulminans was made. DISCUSSION: CONCLUSION:
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Authors | Kazuya Kato, Kazuhiko Onodera, Yoshiaki Iwasaki, Minoru Matsuda, Takako Kawakami, Mineko Higuchi, Kimitaka Kato, Yurina Kato, Masahiko Taniguchi, Hiroyuki Furukawa |
Journal | International journal of surgery case reports
(Int J Surg Case Rep)
Vol. 8C
Pg. 84-7
( 2015)
ISSN: 2210-2612 [Print] Netherlands |
PMID | 25644555
(Publication Type: Journal Article)
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Copyright | Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved. |