Abstract | PURPOSE: The aim of this study was to report the clinical features and management of patients with ocular surface damage during methamphetamine production accidents. METHODS: This is a retrospective noncomparative interventional case series of 5 patients with methamphetamine production-related ocular injuries referred to the Cincinnati Eye Institute between 1999 and 2014. RESULTS: Four of 5 cases were white young men with severe bilateral ocular injury and extremely poor vision. All except 1 eye (9 of 10) were diagnosed with total or near-total ocular surface failure. Limbal stem cell transplantation was performed in 8 of 10 eyes. Keratolimbal allograft was followed by penetrating keratoplasty in 7 of 10 eyes. Ocular surface stability was achieved in 7 of 10 eyes after keratolimabl allograft. Postoperative visual acuity was better than 20/200 in 4 of 10 of eyes. Keratolimbal graft rejection occurred in 3 of 10 eyes; the rate of rejection of penetrating keratoplasty was also 3 out of 10 eyes. CONCLUSIONS:
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Authors | Asadolah Movahedan, Brad M Genereux, Mahshad Darvish-Zargar, Kevin J Shah, Edward J Holland |
Journal | Cornea
(Cornea)
Vol. 34
Issue 4
Pg. 433-7
(Apr 2015)
ISSN: 1536-4798 [Electronic] United States |
PMID | 25642642
(Publication Type: Journal Article)
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Chemical References |
- Central Nervous System Stimulants
- Methamphetamine
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Topics |
- Adult
- Allografts
- Burns, Chemical
(etiology, surgery)
- Central Nervous System Stimulants
(chemical synthesis)
- Corneal Diseases
(etiology, surgery)
- Drug Compounding
(adverse effects)
- Eye Burns
(chemically induced)
- Female
- Follow-Up Studies
- Graft Survival
- Humans
- Keratoplasty, Penetrating
- Limbus Corneae
(cytology)
- Male
- Methamphetamine
(chemical synthesis)
- Retrospective Studies
- Stem Cell Transplantation
- Visual Acuity
(physiology)
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