Adenovirus infection retards ribosomal RNA processing.

Abstract

Eight hours after infection of KB cells with adenovirus type 12, the rate of conversion from the 32S ribosomal RNA (rRNA) precursor to mature 28S and 5.8S rRNA decreased. An additional RNA species was detected, which appears to be novel, on the basis of its estimated size (about 6.5 kilobases) and its high level of radiolabeling early after infection at low multiplicity.

• Authors: S H Lawler, R W Jones, B P Eliceiri, G L Eliceiri
• Journal: Journal of cellular physiology (J Cell Physiol) Vol. 138 Issue 1 Pg. 205-7 (Jan 1989) ISSN: 0021-9541 [Print] United States
• PMID: 2536036 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• RNA, Ribosomal
• RNA, Ribosomal, 28S
• RNA, Ribosomal, 5.8S
• RNA, Small Nuclear

Topics

• Adenoviridae Infections (genetics)
• Animals
• Cell Line
• Gene Expression Regulation
• RNA, Ribosomal (metabolism)
• RNA, Ribosomal, 28S (metabolism)
• RNA, Ribosomal, 5.8S (metabolism)
• RNA, Small Nuclear (metabolism)