Abstract | OBJECTIVES: METHODS: RESULTS: CSCB therapeutic group showed markedly functional recovery by Olby score and spinal somatosensory evoked responses (SSERs) assay at 12 weeks after complete spinal cord transection. Furthermore, numerous peripheral myelinated axons aligned parallel to the long axis of the spinal cord were detected in CSCB group dogs. In stark contrast, the injured site was dominated by fibrous and only scattered axons were detected in the edge of spinal cord in CTL group dogs. CONCLUSION:
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Authors | S Han, B Wang, W Jin, Z Xiao, B Chen, H Xiao, W Ding, J Cao, F Ma, X Li, B Yuan, T Zhu, X Hou, J Wang, J Kong, W Liang, J Dai |
Journal | Spinal cord
(Spinal Cord)
Vol. 52
Issue 12
Pg. 867-73
(Dec 2014)
ISSN: 1476-5624 [Electronic] England |
PMID | 25311846
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Brain-Derived Neurotrophic Factor
- S100 Proteins
- Collagen
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Topics |
- Animals
- Axons
(drug effects)
- Brain-Derived Neurotrophic Factor
(therapeutic use)
- Collagen
(metabolism, therapeutic use)
- Dogs
- Evoked Potentials, Somatosensory
- Female
- Movement
(physiology)
- Myelin Sheath
(drug effects)
- Nerve Regeneration
(drug effects)
- Peripheral Nerves
(drug effects)
- Recovery of Function
- S100 Proteins
(metabolism)
- Spinal Cord Injuries
(drug therapy, pathology)
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