Abstract | BACKGROUND: METHODS: Twenty-four patients with obesity and CP and 24 patients without obesity with CP were submitted to SRP. Clinical parameters were assessed at baseline and 3 and 6 months after therapy. Serum levels of leptin and adiponectin were evaluated at all time points, using enzyme-linked immunosorbent assay. RESULTS: SRP improved the clinical parameters of both groups at 3 and 6 months (P < 0.05). Nonetheless, the patients without obesity presented a lower mean probing depth (PD) at 6 months after therapy and a greater reduction in PD from baseline to 6 months in the full-mouth analysis (primary outcome variable) and in initially deep sites (P < 0.05). Leptin serum levels were higher in patients with obesity than in patients without obesity at all time points (P < 0.05). No changes in the serum levels of leptin and adiponectin were observed in groups with and without obesity after therapy (P > 0.05). CONCLUSIONS: Patients with obesity and CP presented lower reductions in PD than patients without obesity with CP at 6 months after SRP. Furthermore, the treatment did not affect the circulating levels of leptin and adiponectin in any group.
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Authors | Tiago Eduardo Dias Gonçalves, Magda Feres, Glaucia Santos Zimmermann, Marcelo Faveri, Luciene Cristina Figueiredo, Paloma Gralha Braga, Poliana Mendes Duarte |
Journal | Journal of periodontology
(J Periodontol)
Vol. 86
Issue 1
Pg. 53-61
(Jan 2015)
ISSN: 1943-3670 [Electronic] United States |
PMID | 25119561
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Adiponectin
- Blood Glucose
- Leptin
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Topics |
- Adiponectin
(blood)
- Adult
- Aged
- Blood Glucose
(analysis)
- Body Height
- Body Mass Index
- Body Weight
- Chronic Periodontitis
(blood, therapy)
- Dental Plaque
(prevention & control)
- Dental Scaling
(methods)
- Female
- Follow-Up Studies
- Humans
- Leptin
(blood)
- Male
- Middle Aged
- Obesity
(blood, complications)
- Oral Hygiene
(education)
- Periodontal Attachment Loss
(therapy)
- Periodontal Pocket
(therapy)
- Root Planing
(methods)
- Waist Circumference
- Waist-Hip Ratio
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