Abstract | PURPOSE OF REVIEW: We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS: SUMMARY: Rapid diagnosis and early fluid resuscitation are crucial to patients with septic shock, initially with the primary goal to relieve the overt tissue hypoxia. Early fluid therapy is important with the caveat that patients must show an increase in their cardiac output. Beyond 6-12 h further positive fluid balance may not usefully improve tissue oxygenation and may be counterproductive.
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Authors | James J Douglas, Keith R Walley |
Journal | Current opinion in critical care
(Curr Opin Crit Care)
Vol. 20
Issue 4
Pg. 378-84
(Aug 2014)
ISSN: 1531-7072 [Electronic] United States |
PMID | 24979550
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Fluid Therapy
(adverse effects, methods)
- Humans
- Oxygen
(metabolism)
- Resuscitation
- Shock, Septic
(diagnosis, physiopathology, therapy)
- Treatment Outcome
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