Serial FDG PET/CT in autoimmune encephalitis with faciobrachial dystonic seizures.

Abstract

Autoimmune encephalitis (AE) is increasingly recognized as a nonparaneoplastic disorder with autoantibodies to neuronal proteins. Although MRI is frequently unremarkable, PET imaging might contribute to identification of affected brain regions in distinct AE. We report on serial FDG PET in a 72-year-old man with particular AE subtype, with potassium channel complex antibodies and prodromal stage with dystonic seizures. Serial FDG PET/CT revealed that besides limbic structures, basal ganglia are centrally involved and presumably play a key role in the generation of dystonic seizures.

• Authors: Albrecht Kunze, Robert Drescher, Katharina Kaiser, Martin Freesmeyer, Otto W Witte, Hubertus Axer
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 39 Issue 10 Pg. e436-8 (Oct 2014) ISSN: 1536-0229 [Electronic] United States
• PMID: 24566395 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• Fluorodeoxyglucose F18

Topics

• Aged
• Basal Ganglia (diagnostic imaging)
• Brain Diseases (diagnostic imaging)
• Dystonic Disorders (diagnostic imaging)
• Encephalitis
• Fluorodeoxyglucose F18
• Hashimoto Disease (diagnostic imaging)
• Humans
• Limbic System (diagnostic imaging)
• Male
• Multimodal Imaging
• Positron-Emission Tomography
• Radiopharmaceuticals
• Seizures (diagnostic imaging)
• Tomography, X-Ray Computed