Prevalence of metabolic syndrome in type 2 diabetes mellitus using NCEP-ATPIII, IDF and WHO definition and its agreement in Gwalior Chambal region of Central India.

Abstract

UNLABELLED:

The aim of study was to determine the prevalence of metabolic syndrome (MetS) in people with type 2 diabetes mellitus (T2DM). National Cholesterol Education Program (NCEP) ATPIII Criteria, International Diabetes Federation and the World Health Organization (WHO) definitions were used in quantifying the metabolic syndrome and also the concordance between these three criteria's used for identifying metabolic syndrome.

METHODS:

This cross-sectional study involved 700 type 2 diabetic subjects from the urban areas of Gwalior Chambal region (Central India). Subjects in the age group of 28- 87 yrs were included in the study. Type I diabetics, pregnant ladies and those with chronic viral and bacterial infections and serious metabolic disorders were excluded from the study. Fasting blood glucose, Blood lipids (T-cholesterol, triglyceride, HDL-cholesterol) were assessed and anthropometry blood pressure were measured from all the subjects.

RESULTS:

The Prevalence of metabolic syndrome was found to be 45.8%, 57.7% and 28% following NCEP-ATPIII Criteria, IDF and WHO definitions, respectively. Using all the three definitions the prevalence was higher in women in all age groups. ATP III and IDF criteria showed good agreement (k 0.68) compared to ATP III with WHO (k 0.54) and IDF with WHO (k 0.34) criteria. Highest prevalence was observed following IDF definition.

CONCLUSIONS:

A good agreement was observed between ATPIII and IDF criteria. Maximum prevalence of Metabolic syndrome was recorded when IDF criteria was followed. NCEP-ATPIII criteria for the diagnosis of MetS and this criterion reflected equal importance to the every variable and showed a good agreement between the different criteria used.

• Authors: Dhananjay Yadav, Sunil Mahajan, Senthil Kumar Subramanian, Prakash Singh Bisen, Choon Hee Chung, G B K S Prasad
• Journal: Global journal of health science (Glob J Health Sci) Vol. 5 Issue 6 Pg. 142-55 (Sep 17 2013) ISSN: 1916-9736 [Print] Canada
• PMID: 24171882 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Blood Glucose
• Lipids

Topics

• Adult
• Age Factors
• Aged
• Aged, 80 and over
• Blood Glucose
• Blood Pressure
• Body Weights and Measures
• Cross-Sectional Studies
• Diabetes Mellitus, Type 2 (blood, epidemiology)
• Female
• Humans
• India (epidemiology)
• Lipids (blood)
• Male
• Metabolic Syndrome (blood, epidemiology)
• Middle Aged
• Prevalence
• Societies, Medical
• World Health Organization