Abstract | BACKGROUND: Acute endophthalmitis is one of the most serious complications of cataract surgery and often results in severe visual impairment. Several risk factors for acute postoperative endophthalmitis (POE) following cataract surgery have been reported but the level of evidence and strength of association is varied. The purpose of this study was to critically appraise published reports on and to summarize clinical risk factors associated with acute POE which could be easily assessed by ophthalmologists for the introduction and implementation of preventive measure. METHODS: A systematic review and meta-analysis of observational studies was performed. Six databases were searched with no limits on the year or language of publication. Study-specific odds ratios ( Ors) or relative risk (RR) of each risk factor were pooled using a random effect model. RESULTS: CONCLUSIONS: Our study provides summary data on the risk factors for acute POE. Identifying patients at high risk of this sight-threatening eye disease is important from both the public health and clinical perspectives as this would facilitate detection of disease before the onset of irreversible visual loss enabling earlier intervention.
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Authors | He Cao, Lu Zhang, Liping Li, Singkai Lo |
Journal | PloS one
(PLoS One)
Vol. 8
Issue 8
Pg. e71731
( 2013)
ISSN: 1932-6203 [Electronic] United States |
PMID | 23990980
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Topics |
- Acute Disease
- Cataract Extraction
(adverse effects)
- Endophthalmitis
(etiology)
- Humans
- Observational Studies as Topic
- Odds Ratio
- Postoperative Complications
(diagnosis, etiology, prevention & control)
- Risk Factors
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