Identification of human tissue cross-presenting dendritic cells: A new target for cancer vaccines.

Abstract

Dendritic cells (DCs) are a heterogeneous group of functionally specialized antigen-presenting cells. We recently characterized the human tissue cross-presenting DCs and aligned the human and mouse DC subsets. Our findings will facilitate the translation of murine DC studies to the human setting and aid the design of DC-based vaccine strategies for infection and cancer immunotherapy.

• Authors: Muzlifah Haniffa, Matthew Collin, Florent Ginhoux
• Journal: Oncoimmunology (Oncoimmunology) Vol. 2 Issue 3 Pg. e23140 (Mar 01 2013) ISSN: 2162-4011 [Print] United States
• PMID: 23802067 (Publication Type: Journal Article)