[Malaria and children who travel - prophylaxis and therapy].
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| Abstract |
Children account for between 15 - 20 % of all imported malaria cases worldwide. Immigrant children visiting their families in the country of origin in sub-Saharan Africa are at highest risk. Prevention of malaria in children who travel to endemic areas is guided by the ABCD principles - Awareness of risk, Bite prevention, Chemoprophylaxis for high risk areas and rapid Diagnosis and treatment when malaria is suspected. The use of anti-malarial medication in small children is hampered by a paucity of dosage, pharmcokinetic and tolerability data. In the pre-travel consultation parents should be provided with practical advice on anti-mosquito measures, exact, (weight-based) dosages of chemoprophylaxis medication and/or stand-by treatment as indicated. A paediatric formulation is available for daily atovaquone-proguanil chemoprophylaxis (children > 11 kg) and mefloquine is a cost-effective, once weekly prophylaxis that is useful for children > 5 kg who travel for longer periods. The bitter taste of mefloquine should be disguised to increase adherence. When a Stand-by Emergency Treatment (SBET) is indicated, artemether-lumefantrine cherry flavoured dispersible tablets are a good choice for small children. Post-travel to endemic areas, malaria should always be suspected if a child becomes ill. Paediatric malaria is an emergency requiring prompt diagnosis and appropriate treatment.
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| Authors | Patricia Schlagenhauf, Sabine Haller, Noémie Wagner, François Chappuis |
| Journal | Therapeutische Umschau. Revue therapeutique (Ther Umsch) Vol. 70 Issue 6 Pg. 323-33 (Jun 2013) ISSN: 0040-5930 [Print] Switzerland |
| Vernacular Title | Malaria und Kinder, die reisen - Prophylaxe und Therapie. |
| PMID | 23732448 (Publication Type: English Abstract, Journal Article, Review) |
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