[Treatment of neovascular glaucoma].

Abstract

Neovascular glaucoma management is divided into preventive and curative procedures.Pre vention therapy consists of the treatment of the common underlying causes of the disease (ie diabetic retinopathy, ischemic central retinal vein occlusion and ocular ischemic syndrome) as well as the less frequent causes attributed to ocular radiation, ocular tumors, uveitis and other miscellaneous condi tions.Curative therapy includes both the neovascularization treatment and the treatment of the in creased intraocular pressure.lntravitreal Bevacizumab injection enables us to block up the neovascular trigger preparing thereby the pacient to a complement of panretinal photocoagulation or surgical treatment. Since Bevacizumab injection activity is transient, the retinal ischemia treatment by panretinal photocoagulation is mandeited in order to avoid neovascular recurrence.Short term efficacy of Bevacizumab injection is obvious with a constant, marked and swift intraocular pressure lowering espe cially in less severe and/or early forms of the disorder. In more advanced stages of neovascular glaucoma after closing the chamber angle by peripheric anterior synechiae the outcomes of this treatment are inconstant, most of cases necessitating the resorting to surgery (trabeculectomy with antifi brosis drugs or glaucoma drainage implants).

• Authors: D Călugăru, M Călugăru
• Journal: Oftalmologia (Bucharest, Romania : 1990) (Oftalmologia) Vol. 56 Issue 3 Pg. 20-39 ( 2012) ISSN: 1220-0875 [Print] Romania
• Vernacular Title: Tratamentul glaucomului neovascular.
• PMID: 23713336 (Publication Type: English Abstract, Journal Article)

Chemical References

• Angiogenesis Inhibitors
• Antibodies, Monoclonal, Humanized
• Bevacizumab

Topics

• Angiogenesis Inhibitors (administration & dosage)
• Antibodies, Monoclonal, Humanized (administration & dosage)
• Bevacizumab
• Diagnosis, Differential
• Early Diagnosis
• Evidence-Based Medicine
• Glaucoma Drainage Implants
• Glaucoma, Neovascular (diagnosis, etiology, prevention & control, therapy)
• Humans
• Intraocular Pressure (drug effects)
• Intravitreal Injections
• Light Coagulation (methods)
• Risk Factors
• Trabeculectomy (methods)
• Treatment Outcome