[New perspectives in monitoring of exposures to carcinogens].

Abstract

Biomonitoring occupational and environmental exposures to carcinogens is a common practice and several biomarkers have been developed for risk assessment. However, in particular, because of the lack of prospective studies, the place of these biomarkers within the complex scenario of the gene-environment interactions leading to cancer cannot be defined. New opportunities and suggestions for biomonitoring exposures to carcinogens could derive from exploring the exposome, from the results of genomewide association and omic studies. Based on these premises it is possible to envisage personalized biomonitoring procedures, as those already actuated in nutrition and clinical oncology, allowing a better predictivity of biomarkers in the preventive settings.

• Authors: Sofia Pavanello, Marcello Lotti
• Journal: Giornale italiano di medicina del lavoro ed ergonomia (G Ital Med Lav Ergon) 2011 Jul-Sep Vol. 33 Issue 3 Suppl Pg. 88-91 ISSN: 1592-7830 [Print] Italy
• Vernacular Title: Nuove prospettive nel monitoraggio delle esposizioni a cancerogeni.
• PMID: 23393809 (Publication Type: English Abstract, Journal Article)

Chemical References

• Carcinogens

Topics

• Carcinogens
• Environmental Exposure (adverse effects)
• Environmental Monitoring
• Humans
• Occupational Exposure (adverse effects)