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Effects of the cannabinoid-1 receptor antagonist/inverse agonist rimonabant on satiety signaling in overweight people with schizophrenia: a randomized, double-blind, pilot study.

AuthorsKimberly R Warren, Robert W Buchanan, Stephanie Feldman, Robert R Conley, Jared Linthicum, Mary Patricia Ball, Fang Liu, Robert P McMahon, David A Gorelick, Marilyn A Huestis, Deanna L Kelly
JournalJournal of clinical psychopharmacology (J Clin Psychopharmacol) Vol. 33 Issue 1 Pg. 118-20 (Feb 2013) ISSN: 1533-712X [Electronic] United States
PMID23277241 (Publication Type: Letter, Randomized Controlled Trial, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural)
Chemical References
  • Antipsychotic Agents
  • Appetite Depressants
  • CNR1 protein, human
  • Cannabinoid Receptor Antagonists
  • Piperidines
  • Pyrazoles
  • Receptor, Cannabinoid, CB1
  • Rimonabant
Topics
  • Adult
  • Antipsychotic Agents (adverse effects)
  • Appetite Depressants (adverse effects, therapeutic use)
  • Body Mass Index
  • Body Weight (drug effects)
  • Brain (drug effects, metabolism)
  • Cannabinoid Receptor Antagonists (adverse effects, therapeutic use)
  • Double-Blind Method
  • Drug Inverse Agonism
  • Eating (drug effects)
  • Energy Intake (drug effects)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Overweight (chemically induced, diagnosis, drug therapy, psychology)
  • Pilot Projects
  • Piperidines (adverse effects, therapeutic use)
  • Pyrazoles (adverse effects, therapeutic use)
  • Receptor, Cannabinoid, CB1 (antagonists & inhibitors, metabolism)
  • Rimonabant
  • Satiety Response (drug effects)
  • Schizophrenia (diagnosis, drug therapy)
  • Schizophrenic Psychology
  • Signal Transduction (drug effects)
  • Treatment Outcome

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