Abstract | BACKGROUND: METHODS: RESULTS: In all groups, piritramide consumption was high in PACU. Only metamizol significantly reduced piritramide consumption compared to the others upon discharge from PACU. Overall, cumulative piritramide consumption was slightly lower in the metamizol group and higher in the NaCl group; however, these findings were statistically not significant. VAS scores were highest upon arrival in PACU and dropped almost continuously after surgery. A significantly lower postoperative pain intensity was only found in the parecoxib group at 24 h after surgery compared to the metamizol group. CONCLUSION: The efficacy of tested additive medications on piritramide consumption and pain relief is weak and there is no clear-cut difference between the non- opioid drugs used.
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Authors | S Abdulla, R Eckhardt, U Netter, W Abdulla |
Journal | Acta anaesthesiologica Belgica
(Acta Anaesthesiol Belg)
Vol. 63
Issue 1
Pg. 43-50
( 2012)
ISSN: 0001-5164 [Print] Belgium |
PMID | 22783709
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics
- Analgesics, Opioid
- Isoxazoles
- Acetaminophen
- Pirinitramide
- Dipyrone
- parecoxib
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Topics |
- Acetaminophen
(administration & dosage, therapeutic use)
- Adult
- Aged
- Analgesia, Patient-Controlled
(methods)
- Analgesics
(administration & dosage, therapeutic use)
- Analgesics, Opioid
(administration & dosage, therapeutic use)
- Cholecystectomy, Laparoscopic
(methods)
- Dipyrone
(administration & dosage, therapeutic use)
- Double-Blind Method
- Drug Therapy, Combination
- Female
- Humans
- Isoxazoles
(administration & dosage, therapeutic use)
- Male
- Middle Aged
- Pain Measurement
- Pain, Postoperative
(drug therapy)
- Pirinitramide
(administration & dosage, therapeutic use)
- Treatment Outcome
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