Abstract |
Numerous plant species worldwide including Palicourea marcgravii and Tanaecium bilabiatum in Brazil cause sudden death and are known to contain monofluoroacetate (MFA). Other species in Brazil including some species traditionally assigned to Mascagnia but now properly called Amorimia species and other Palicourea species are reported to cause sudden death in livestock and are suspected to contain MFA due to the similarity of clinical signs. In this study, an HPLC-APCI-MS method to detect and quantify MFA was developed and was used to investigate plant material from field collections and/or herbarium specimens of Mascagnia, Amorimia, and Palicourea species suspected of causing sudden death. MFA was detected in Amorimia amazonica, Amorimia camporum, Amorimia exotropica, Amorimia pubiflora, Amorimia rigida, and Amorimia septentrionalis as well as Palicourea aeneofusca. MFA concentrations differ greatly between Palicourea species and Amorimia species, which may explain the incidence of poisoning and the amount of plant material required to cause sudden death between these taxa.
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Authors | Stephen T Lee, Daniel Cook, Franklin Riet-Correa, James A Pfister, William R Anderson, Flavia G Lima, Dale R Gardner |
Journal | Toxicon : official journal of the International Society on Toxinology
(Toxicon)
Vol. 60
Issue 5
Pg. 791-6
(Oct 2012)
ISSN: 1879-3150 [Electronic] England |
PMID | 22699106
(Publication Type: Journal Article)
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Copyright | Published by Elsevier Ltd. |
Chemical References |
- Fluoroacetates
- fluoroacetic acid
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Topics |
- Brazil
- Chromatography, High Pressure Liquid
- Fluoroacetates
(analysis)
- Malpighiaceae
(chemistry)
- Mass Spectrometry
- Plant Leaves
(chemistry)
- Plants, Toxic
(chemistry)
- Rubiaceae
(chemistry)
- Species Specificity
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