Dietary antioxidants and periodontal disease in community-based older Japanese: a 2-year follow-up study.

Abstract

OBJECTIVE:

To investigate the longitudinal relationship between the intake of dietary antioxidants and periodontal disease in community-dwelling older Japanese.

DESIGN:

A retrospective cohort study, with a follow-up of 2 years (2003-2005). Intakes of dietary antioxidants (vitamin C, vitamin E, α-carotene and β-carotene) were assessed with a validated FFQ. Participants were classified by tertile of antioxidant intake. Full-mouth periodontal status, measured as the clinical attachment level, was recorded at baseline and follow-up examinations. Periodontal disease progression was considered as loss of attachment of 3 mm or greater over the study period at the interproximal site for each tooth. Finally, the number of teeth with periodontal disease progression per person was calculated and was used as the outcome. Poisson regression analysis was conducted, with dietary antioxidants as the main exposure, to estimate their influence on the number of teeth with periodontal disease progression.

SETTING:

Niigata City (Japan).

SUBJECTS:

Dentate individuals aged 75 years in 2003, for whom data were available, were included in the analyses (n 264).

RESULTS:

A higher intake of dietary antioxidants was inversely associated with the number of teeth with periodontal disease progression, controlling for other variables. The multivariate-adjusted incidence rate ratios in the first, second and third tertiles were 1·00, 0·76 (95 % CI 0·60, 0·97) and 0·72 (95 % CI 0·56, 0·93) for vitamin C; 1·00, 0·79 (95 % CI 0·62, 0·99) and 0·55 (95 % CI 0·42, 0·72), for vitamin E; and 1·00, 1·02 (95 % CI 0·81, 1·29) and 0·73 (95 % CI 0·56, 0·95) for β-carotene.

CONCLUSIONS:

The study results suggest that higher intake of antioxidants may mitigate periodontal disease in community-dwelling older Japanese.

• Authors: Masanori Iwasaki, Paula Moynihan, Michael C Manz, George W Taylor, Akihiro Yoshihara, Kanako Muramatsu, Reiko Watanabe, Hideo Miyazaki
• Journal: Public health nutrition (Public Health Nutr) Vol. 16 Issue 2 Pg. 330-8 (Feb 2013) ISSN: 1475-2727 [Electronic] England
• PMID: 22613693 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antioxidants
• beta Carotene
• Vitamin E
• Carotenoids
• alpha-carotene
• Ascorbic Acid

Topics

• Aged
• Antioxidants (pharmacology, therapeutic use)
• Ascorbic Acid (pharmacology, therapeutic use)
• Carotenoids (pharmacology, therapeutic use)
• Disease Progression
• Female
• Follow-Up Studies
• Humans
• Incidence
• Japan (epidemiology)
• Male
• Multivariate Analysis
• Periodontal Diseases (diet therapy, epidemiology)
• Periodontium (drug effects)
• Poisson Distribution
• Retrospective Studies
• Surveys and Questionnaires
• Tooth (drug effects)
• Vitamin E (pharmacology, therapeutic use)
• beta Carotene (pharmacology, therapeutic use)