[The importance of benziodarone in the treatment of gout and hyperuricemic syndrome].

Abstract

The authors pay attention to benziodarone, a representative of the category of benzofurans. They test its effect on the uric acid serum level in normouraemic subjects as well as in hyperuricaemic syndrome and gouty arthritis. The hypouricaemic action of benziodarone (Amplivex-Labaz) is prompt. The maximum drop of uricaemia after Amplivex administration (2 tablets/day) occurs during the first three days. The uric acid level declines by as much as 80% of the baseline value. For long-term treatment 1 tablet per day is sufficient, in some instances even 1 tablet twice a week. The tolerance of the preparation is satisfactory. The authors deal also with the mechanism of action of benziodarone. Amplivex is not only a uricostatic but also a uricosuric agent.

• Authors: M Lindusková, M Vykydal
• Journal: Casopis lekaru ceskych (Cas Lek Cesk) Vol. 129 Issue 48 Pg. 1524-5 (Nov 30 1990) ISSN: 0008-7335 [Print] Czech Republic
• Vernacular Title: Význam benziodaronu v lécbĕ dny a hyperurikemického syndromu.
• PMID: 2257602 (Publication Type: English Abstract, Journal Article)

Chemical References

• Benzofurans
• Uricosuric Agents
• Uric Acid
• benziodarone

Topics

• Arthritis, Gouty (blood, drug therapy)
• Benzofurans (therapeutic use)
• Female
• Humans
• Male
• Uric Acid (blood)
• Uricosuric Agents (therapeutic use)