Successful treatment of imported mucosal Leishmania infantum leishmaniasis with miltefosine after severe hypokalemia under meglumine antimoniate treatment.

Abstract

Old World mucosal leishmaniasis is a rare but regularly reported disease in Southern Europe. We report the case of a 64-year-old woman who developed severe hypokalemia under meglumine antimoniate treatment and was successfully treated under second line therapy with miltefosine.

• Authors: Andreas L C Neumayr, Clemens Walter, Marcel Stoeckle, Natalie Braendle, Kathrin Glatz, Johannes A Blum
• Journal: Journal of travel medicine (J Travel Med) 2012 Mar-Apr Vol. 19 Issue 2 Pg. 124-6 ISSN: 1708-8305 [Electronic] England
• PMID: 22414039 (Publication Type: Journal Article)
• Copyright: © 2011 International Society of Travel Medicine.

Chemical References

• Anti-Allergic Agents
• Antiprotozoal Agents
• Organometallic Compounds
• Phosphorylcholine
• miltefosine
• Meglumine
• Meglumine Antimoniate
• Potassium

Topics

• Animals
• Anti-Allergic Agents (therapeutic use)
• Antiprotozoal Agents (administration & dosage, adverse effects)
• Arrhythmias, Cardiac (diagnosis, etiology)
• Biopsy
• Drug Administration Routes
• Drug Substitution
• Electrocardiography
• Endemic Diseases
• Exanthema (chemically induced, therapy)
• Female
• Greece
• Humans
• Hypokalemia (blood, chemically induced, complications, therapy)
• Insect Vectors
• Italy
• Leishmania infantum (drug effects, isolation & purification)
• Leishmaniasis, Visceral (complications, diagnosis, drug therapy, physiopathology, transmission)
• Meglumine (administration & dosage, adverse effects)
• Meglumine Antimoniate
• Middle Aged
• Morocco
• Mouth Mucosa (pathology)
• Oral Ulcer (drug therapy, etiology, pathology, physiopathology)
• Organometallic Compounds (administration & dosage, adverse effects)
• Phosphorylcholine (administration & dosage, adverse effects, analogs & derivatives)
• Potassium (blood, therapeutic use)
• Psychodidae
• Spain
• Travel
• Treatment Outcome