Abstract | INTRODUCTION AND PURPOSE: METHODS: Patients with clinical symptoms of UNE and a nerve conduction study compatible with UNE or thickened ulnar nerve at the elbow (> 10 mm(2)) by ultrasonography were included. All included patients received an ultrasound-guided injection of 1 ml containing 40 mg methylprednisoloneacetate and 10 mg lidocainhydrochloride ( Depo-Medrol(®)). Complications of the injection were monitored. After 3 months, nerve conduction studies and ultrasonography were repeated and a clinical outcome determined. RESULTS: Eight patients with nine UNE were included. None of the patients mentioned increase in the symptoms directly after the injection nor had an infection on the injection site or haematoma. After 3 months, there was improvement of the symptoms in five patients. One patient deteriorated and three had no change of the symptoms at all. Overall, there was no significant change of the thickness of the ulnar nerve with mean difference -0.056 mm(2) (95% CI -2.56 to 2.45 mm(2)). CONCLUSION: We showed that injection with corticosteroids in patients with UNE is easy and safe, and based on this result, we found enough arguments to launch a prospective, placebo-controlled trial to explore the effectiveness of corticosteroids in patients with UNE.
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Authors | C L Alblas, V van Kasteel, K Jellema |
Journal | European journal of neurology
(Eur J Neurol)
Vol. 19
Issue 12
Pg. 1582-4
(Dec 2012)
ISSN: 1468-1331 [Electronic] England |
PMID | 22339768
(Publication Type: Clinical Trial, Journal Article)
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Copyright | © 2012 The Author(s) European Journal of Neurology © 2012 EFNS. |
Chemical References |
- Adrenal Cortex Hormones
- Methylprednisolone Acetate
- Methylprednisolone
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Topics |
- Adrenal Cortex Hormones
(administration & dosage)
- Adult
- Aged
- Elbow
- Feasibility Studies
- Female
- Humans
- Injections, Subcutaneous
(methods)
- Male
- Methylprednisolone
(administration & dosage, analogs & derivatives)
- Methylprednisolone Acetate
- Middle Aged
- Ulnar Neuropathies
(diagnostic imaging, drug therapy)
- Ultrasonography, Interventional
(methods)
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