Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution.
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| Abstract | BACKGROUND: T1 and T2 tonsillar squamous cell cancer with limited neck disease can be managed with single-modality radiation or surgery. Over 11 years, 17 patients underwent radical tonsillectomies; and 33 patients underwent radiation-based treatments for T1 and T2 and N0 to N2a tonsil cancer. Patients were intended to receive single-modality treatment based on presentation; however, some ultimately received adjuvant treatments. METHODS: A retrospective chart review to compare overall survival (OS), disease-specific survival (DSS), and locoregional control (LRC) between the groups was used. RESULTS: In surgical group, of 17 patients, 11 underwent surgery alone, 3 underwent surgery and radiation, and 3 underwent surgery with concurrent chemoradiation. Five-year OS for the surgical and radiation groups was 93% and 72%, respectively (no significance achieved). Five-year DSS rates (93% and 80%) and LRC (69% and 89%) similarly did not yield any significant difference. CONCLUSION: Surgery remains a viable option in the management of T1 and T2 tonsillar cancers with comparable LRC, OS, and DSS.
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| Authors | Eric D Lamarre, Rahul Seth, Robert R Lorenz, Ramon Esclamado, David J Adelstein, Cristina P Rodriguez, Jerrold Saxton, Joseph Scharpf |
| Journal | American journal of otolaryngology (Am J Otolaryngol) 2012 Jan-Feb Vol. 33 Issue 1 Pg. 98-103 ISSN: 1532-818X [Electronic] United States |
| PMID | 21696857 (Publication Type: Comparative Study, Journal Article) |
| Copyright | Copyright © 2012 Elsevier Inc. All rights reserved. |
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