[Ephedron dependence--case report].

Abstract

Ephedrone (Methcathinone), a derivative of phenylpropan, (2-(methylamino)-1-phenylpropan-1-one) is synthesised from ephedrine or pseudoephedrine by potassium permanganate oxidation. It has been demonstrated that ephedrone stimulates central nervous system and inhibits dopamine and norepinephrine re-uptake. The authors described the case of a 32-years-old patient, who has been addicted to ephedrone for three years. The case was compared with other articles. Attention was drawn to the growing problem of ephedrone addiction, which is often used as an easier to obtain and cheaper replacement of amphetamine. The risk arising from the intravenous route of ephedrone administration, as well as the potential for manganese poisoning were highlighted. Inconsistency of the existing legislation was also shown, which is prohibiting the use of Catha edulis derivatives and not regulating disposal of substances, which are precursors of psychoactive and addictive ephedrone.

• Authors: Dominika Myślicka, Marta Zuk, Maciej Dziurkowski
• Journal: Psychiatria polska (Psychiatr Pol) 2011 Jan-Feb Vol. 45 Issue 1 Pg. 79-85 ISSN: 0033-2674 [Print] Poland
• Vernacular Title: Uzaleznienie od efedronu--opis przypadku.
• PMID: 21614834 (Publication Type: Case Reports, Journal Article)

Chemical References

• Central Nervous System Stimulants
• Illicit Drugs
• Ephedrine

Topics

• Adult
• Behavior, Addictive (complications, diagnosis)
• Central Nervous System Stimulants (poisoning)
• Ephedrine (poisoning)
• Humans
• Illicit Drugs (poisoning)
• Injections, Intravenous (adverse effects)
• Male
• Manganese Poisoning (etiology)
• Risk Factors
• Substance Abuse Detection (methods)
• Substance Abuse, Intravenous (complications, diagnosis, prevention & control)