Endovascular treatment of patients with types A and B thoracic aortic dissection using Relay thoracic stent-grafts: results from the RESTORE Patient Registry.

Abstract

PURPOSE:

To evaluate the safety and performance of Relay stent-grafts in patients with acute or chronic aortic dissections.

METHODS:

Patients with types A or B aortic dissections suitable for treatment with Relay stent-grafts and followed for 2 years after thoracic endovascular aortic repair (TEVAR) were identified from a company-sponsored registry database established in January 2006. Ninety-one consecutive patients (69 men; mean age 65 years) underwent TEVAR with Relay stent-grafts for dissection. Most patients (76, 84%) had type B dissections; 61 of all patients were classified as chronic and 30 as acute.

RESULTS:

The technical success rate was 95% (97% in acute, 95% in chronic, and 93% in type B dissections). The type I endoleak rate was 7% (7% in acute and 8% in chronic dissections); all occurred in patients with type B dissections. Paraplegia, paraparesis, and stroke occurred in 4, 1, and 2 patients, respectively; 2 cases of paraplegia occurred in patients with acute type B dissections. Thirty-day mortality was 8% (13% in acute and 5% in chronic dissections); all deaths occurred in patients with type B dissections. The 2-year survival rate was 82% in the overall population and 84% in patients with type B dissections.

CONCLUSION:

The combination of Relay's features, such as stent conformability, radial force, atraumatic design, and controlled deployment and fixation, may contribute to the safety of the Relay stent-grafts for the treatment of thoracic aortic dissections, including acute and chronic type B dissections.

• Authors: Burkhart Zipfel, Martin Czerny, Martin Funovics, Gioacchino Coppi, Carlo Ferro, Hervé Rousseau, Sergio Berti, Domenico G Tealdi, Vincent Riambau, Nicola Mangialardi, Carlo Sassi, RESTORE Investigators
• Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists (J Endovasc Ther) Vol. 18 Issue 2 Pg. 131-43 (Apr 2011) ISSN: 1545-1550 [Electronic] United States
• PMID: 21521051 (Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)

Topics

• Acute Disease
• Adult
• Aged
• Aged, 80 and over
• Aortic Dissection (diagnosis, mortality, surgery)
• Aortic Aneurysm, Thoracic (diagnosis, mortality, surgery)
• Aortography (methods)
• Blood Vessel Prosthesis
• Blood Vessel Prosthesis Implantation (adverse effects, instrumentation, mortality)
• Chi-Square Distribution
• Chronic Disease
• Endoleak (etiology)
• Endovascular Procedures (adverse effects, instrumentation, mortality)
• Europe
• Female
• Humans
• Kaplan-Meier Estimate
• Magnetic Resonance Angiography
• Male
• Middle Aged
• Paraparesis (etiology)
• Paraplegia (etiology)
• Patient Selection
• Prosthesis Design
• Registries
• Risk Assessment
• Risk Factors
• Stents
• Stroke (etiology)
• Survival Rate
• Time Factors
• Tomography, X-Ray Computed
• Treatment Outcome